abstract：INTRODUCTION:An increased risk of mortality in patients with uncontrolled acromegaly has been reported in several studies. We aimed to assess the impact of co-morbidities on the survival of patients with acromegaly after long-term treatment and follow-up. MATERIAL AND METHODS:A retrospective analysis was performed for...

journal_title：Endokrynologia Polska

authors： Wen-Ko C,Szu-Tah C,Feng-Hsuan L,Chen-Nen C,Ming-Hsu W,Jen-Der L

更新日期：2016-01-01 00:00:00

abstract：:Ig-G4 related disease (IgG4RD) is a heterogeneous disorder with multi-organ involvement recognised as a separate entity at the start of this century only. It is currently one of the hottest areas of clinical and translational research across specialties. Thyroid involvement in IgG4RD is rare, believed to occur in less...

journal_title：Endokrynologia Polska

authors： Dutta D,Ahuja A,Selvan C

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:After thyroidectomy and radioiodine therapy, patients with differentiated thyroid cancer (DTC) are indefinitely treated with levothyroxine (L-T4). Osteoporosis is a debated consequence of hypothyroxinaemia. The aim of this study was to evaluate bone mineral density (BMD) and fracture risk assessed by FRAX ...

journal_title：Endokrynologia Polska

authors： Vera L,Gay S,Campomenosi C,Paolino S,Pera G,Monti E,Mortara L,Seriolo B,Giusti M

更新日期：2016-01-01 00:00:00

abstract：:The present study is aimed to present the potential role of thyroid hormones (TH) in the pathogenesis of glioblastoma multiforme (GBM). In first part of this presentation the effect of general homeostasis of TH on GBM formation and course was shown. Then the evidence concerning present state of the knowledge about act...

journal_title：Endokrynologia Polska

authors： Nauman P

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:Vitamin D receptor (VDR) is encoded by the VDR gene. Several studies have supported that this gene is associated with diabetes. Heterodimer VDR/RXR functions as an enhancer of the BGLAP gene and increases the basal transcription rate of osteocalcin (OC) during osteoblast differentiation. OC is a regulator ...

journal_title：Endokrynologia Polska

authors： Rivera-Leon EA,Palmeros-Sanchez B,Llamas-Covarrubias IM,Fernandez S,Armendariz-Borunda J,Gonzalez-Hita M,Bastidas-Ramirez BE,Zepeda-Moreno A,Sanchez-Enriquez S

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:Hypolipidaemic agents were found to affect plasma adipokine levels, but no previous study has investigated whether this effect is sex-dependent. MATERIAL AND METHODS:We retrospectively analysed 61 patients participating in our previous studies, who because of isolated hypercholesterolaemia were treated wi...

journal_title：Endokrynologia Polska

authors： Krysiak R,Żmuda W,Marek B,Okopień B

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:Chronic psychological distress can cause suppression of the hypothalamic-pituitary-testicular axis and thus lead to male hypogonadism, which is associated with psycho-social dysfunction, chronic diseases, and as a result, considerable economic costs. Conversely, noise is a prototypal environmental stressor...

journal_title：Endokrynologia Polska

authors： Dzhambov A,Dimitrova D

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:Secondary hyperparathyroidism (sHPT) is one of the most common abnormalities found in patients with chronic kidney disease (CKD). Measurement of serum PTH concentrations is crucial in diagnosis and treatment of sHPT. Different methods of serum PTH measurement may provide diverse results. This may have a si...

journal_title：Endokrynologia Polska

authors： Kuczera P,Maszczyk A,Machura E,Kurzak E,Adamczak M,Więcek A

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:Omentin-1, secreted by visceral adipose tissue, has been indicated in the regulation of bone metabolism in girls with anorexia nervosa (AN). The aim of the study was to evaluate the relationship between omentin-1 and bone metabolism in girls with AN as well as the potential involvement of OPG and RANKL in ...

journal_title：Endokrynologia Polska

authors： Gołąbek K,Ostrowska Z,Ziora K,Oświęcimska J,Świętochowska E,Marek B,Kajdaniuk D,Strzelczyk J,Kos-Kudła B

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:Growth hormone (GH) deficiency, either isolated or combined with other pituitary hormone deficiencies, is associated with increased mortality and abnormal body composition, particularly visceral adiposity. We aimed to investigate the effects of GH deficiency with or without sex steroid deficiencies on ultr...

journal_title：Endokrynologia Polska

authors： Topaloglu O,Gokay F,Koparal SS,Akbaba G,Mete T,Arduc A,Tuna MM,Yalcin Y,Yavuz HC,Berker D,Guler S

更新日期：2014-01-01 00:00:00

abstract：INTRODUCTION:To assess in a prospective study the course and the predictors of microalbuminuria in children and adolescents with type 1 diabetes. MATERIAL AND METHODS:438 children and adolescents who developed diabetes in the years 1985-2004 were followed for 9.2 ± 3.4 years from the diagnosis. Microalbuminuria was as...

journal_title：Endokrynologia Polska

authors： Nazim J,Fendler W,Starzyk J

更新日期：2014-01-01 00:00:00

abstract：INTRODUCTION:Fine needle aspiration biopsy (FNAB) is the main examination in diagnostics of thyroid nodules. Yet, it does not allow the differentiation of follicular lesions (FL). A new classification of thyroid biopsy results (newC) might improve pre-operative diagnostics mainly due to the introduction of a new subcat...

journal_title：Endokrynologia Polska

authors： Woźniak-Oseła E,Popowicz B,Sporny S,Klencki M,Słowińska-Klencka D

更新日期：2014-01-01 00:00:00

abstract：:Autoimmune polyglandular syndromes (APS) consist of a variety of endocrine and non-endocrine disorders. The syndromes are complex and their occurrence in life does not follow any pattern. Early detection of such disorders may prevent many serious clinical consequences which are usually a result of delayed diagnosis. W...

journal_title：Endokrynologia Polska

authors： Barg E,Skarżynska M,Pollak A,Ślęzak R,Głąb E,Petriczko E,Józwa A,Sąsiadek MM

更新日期：2014-01-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to determine whether girls with anorexia nervosa (AN) exhibited any relationships between serum levels of LP, ADIPO, RES, VISF, APE-36, APE-12, and bone markers, OPG and sRANKL. MATERIAL AND METHODS:Serum levels of selected adipose tissue hormones, OC, CTx, OPG and sRANKL were as...

journal_title：Endokrynologia Polska

authors： Ostrowska Z,Ziora K,Oświęcimska J,Świętochowska E,Marek B,Kajdaniuk D,Wołkowska-Pokrywa K,Kos-Kudła B

更新日期：2014-01-01 00:00:00

abstract：:The treatment of Graves' orbitopathy (GO) remains a diagnostic and therapeutic challenge for clinicians worldwide. The elimination of risk factors, such as encouraging smoking cessation and achieving euthyroidism, are the most important and usually sufficient treatment methods in most mild cases. A course of selenium ...

journal_title：Endokrynologia Polska

authors： Ruchała M,Hernik A,Zybek A

更新日期：2014-01-01 00:00:00

abstract：INTRODUCTION:In the current study, we evaluated the accuracy of sentinel node mapping in thyroid cancer patients using both radiotracer and blue dye. MATERIAL AND METHODS:30 patients with a diagnosis of papillary thyroid carcinoma (PTC) were included in the study; 2-3 hours before surgery, 0.5 mCi 99m-Tc-Antimony Sulf...

journal_title：Endokrynologia Polska

authors： Assadi M,Yarani M,Zakavi SR,Jangjoo A,Memar B,Treglia G,Aliakbarian M,Mehrabibahar M,Sadeghi R

更新日期：2014-01-01 00:00:00

abstract：INTRODUCTION:The influence of adolescent obesity on weight loss following bariatric surgery in adults has not been evaluated. The purpose of this study was to determine the impact of prior adolescent obesity on long-term weight changes following Roux-en-Y gastric bypass (RYGB) in adulthood. MATERIAL AND METHODS:This s...

journal_title：Endokrynologia Polska

authors： Durczynski A,Szymanski D,Nowicki M,Hogendorf P,Chalubinska-Fendler J,Wojciechowska-Durczynska K,Czupryniak L,Strzelczyk J

更新日期：2013-01-01 00:00:00

abstract：:Thyroid disorders are more frequently observed in diabetic patients. These conditions have been shown to be mainly of autoimmune origin and all of them may lead to hormonal imbalance. Especially strong links exist between autoimmune thyroid diseases (AITD) and type 1 diabetes. Importantly, both hypothyroidism and hype...

journal_title：Endokrynologia Polska

authors： Sowiński J,Czupryniak L,Milewicz A,Hubalewska-Dydejczyk A,Szelachowska M,Ruchała M,Lewiński A,Górska M,Siewko K,Wender-Ożegowska E,Zozulińska-Ziółkiewicz D,Junik R,Sawicka N,Gutaj P,Polish Society of Endocrinology.,Polish D

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:Bone disorders observed commonly after haematopoietic stem cells transplantation (HSCT) can be caused by several factors,but their detailed pathomechanism is still not well known, especially in childhood.The aim of this study was to evaluate: IGF-I, RANKL-OPG system, IL-6, and IL1β levels and their associa...

journal_title：Endokrynologia Polska

authors： Wędrychowicz A,Sztefko K,Majka M,Ratajczak MZ

更新日期：2013-01-01 00:00:00

abstract：:Primary aldosteronism is the commonest form of hormone-related hypertension, with an estimated prevalence of 6-13% in the generalpopulation of hypertensive patients. Among patients with resistant hypertension, the proportion of PA is even higher. Through intensiveresearch in the field of basic science and the creation...

journal_title：Endokrynologia Polska

authors： Kołodziejczyk-Kruk S,Januszewicz W,Pęczkowska M,Prejbisz A,Zgliczyński W,Januszewicz A

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:Childhood obesity has been associated with the development of insulin resistance, potentially leading to several metabolic disorders. Osteocalcin has been reported to contribute to the regulation of glucose tolerance and insulin sensitivity. The purpose of this study was to examine the relationship between...

journal_title：Endokrynologia Polska

authors： Garanty-Bogacka B,Syrenicz M,Rać M,Krupa B,Czaja-Bulsa G,Walczak M,Sowińska-Przepiera E,Syrenicz A

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:Over the last decade, average life expectancy has continuously increased. There has been no data on normal sex hormone (SH) levels in a Polish elderly population. In this study, we assessed SH in the PolSenior cohort to determine normal reference ranges in relation to gender, age, and cardiovascular diseas...

journal_title：Endokrynologia Polska

authors： Milewicz A,Krzyżanowska-Świniarska B,Miazgowski T,Jędrzejuk D,Arkowska A,Mieszczanowicz U,Bar-Andziak E

更新日期：2013-01-01 00:00:00

abstract：:Cushing's disease (CD) is caused by an adrenocorticotrophin (ACTH) secreting pituitary adenoma and it is the commonest cause of endogenous hypercortisolism. When high suspicion of Cushing's syndrome (CS) exists, recommended screening tests include the overnight dexamethasone suppression test, the low-dose dexamethason...

journal_title：Endokrynologia Polska

authors： Juszczak A,Grossman A

更新日期：2013-01-01 00:00:00

abstract：:Neuroendocrine neoplasms of the large intestine account for 20% of all neuroendocrine neoplasms (NENs) and are most commonly found in the rectum. The rate of detection of colorectal NENs is increasing, and this tendency will continue due to the widespread use of colonoscopy as a screening tool and the removal of all d...

journal_title：Endokrynologia Polska

authors： Starzyńska T,Deptała A,Królicki L,Kunikowska J,Londzin-Olesik M,Nasierowska-Guttmejer A,Ruchała M,Strzelczyk J,Szawłowski A,Zgliczyński W,Kos-Kudła B,Consensus Conference.,Polish Network of Neuroendocrine Tumours.

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:Thyroid hormone disorders in patients with chronic kidney disease (CKD) are a result of impaired conversion of T4 to T3. The importance of kidneys in thyroid hormones conversion is not fully understood. The activities of different types of iodothyronine deiodinases in the kidney structures have not been de...

journal_title：Endokrynologia Polska

authors： Niemczyk S,Dudek M,Bartoszewicz Z,Szamotulska K,Woźniacki L,Brodowska-Kania D,Niemczyk L,Małek W,Matuszkiewicz-Rowińska J

更新日期：2013-01-01 00:00:00

abstract：:Increased interest in vitamin D measurements in clinical studies has contributed to the development in recent years of several new immunochemical assays (manual and for automatic analyzers). New methods, including HPLC (high performance liquid chromatography), and LC-MS/MS (liquid chromatography coupled with tandem ma...

journal_title：Endokrynologia Polska

authors： Bartoszewicz Z,Kondracka A,Jaźwiec R,Popow M,Dadlez M,Bednarczuk T

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:Iron overload is a major problem in patients with b-thalassemia major, and it has many structural and metabolic consequences. In this study, we aimed to consider the prevalence of endocrine abnormalities in patients with β-thalassemia major and thalassemia intermedia. MATERIALS AND METHODS:We ordered foll...

journal_title：Endokrynologia Polska

authors： Kurtoglu AU,Kurtoglu E,Temizkan AK

更新日期：2012-01-01 00:00:00

abstract：:In view of the fact that primary aldosteronism (PA) is a problem that is more prevalent than previously thought and its diagnosis is of greater clinical significance than previously believed, the Endocrine Society has recently published recommendations on the diagnosis and management of PA. Due to the fact that the cu...

journal_title：Endokrynologia Polska

authors： Myśliwiec J,Górska M

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:The overexpression of nitric oxide synthase (NOS) has been found in tumours, including pituitary adenomas. It has also been found that NOS is overexpressed in human spontaneous pituitary adenomas. The question arises whether NOS and its product, nitric oxide (NO), are involved in pituitary tumourigenesis. ...

journal_title：Endokrynologia Polska

authors： Pawlikowski M,Pisarek H,Fryczak J,Stępień H

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:In this study, we aimed to investigate the relationship between glycated haemoglobin (HbA1c) levels and the severity of coronary artery disease (CAD) in < 40 years old patients. MATERIAL AND METHODS:The study population consisted of 211 premature coronary atherosclerotic patients (pCAP) (aged 36.4 ± 2.5 y...

journal_title：Endokrynologia Polska

authors： Ayhan SS,Tosun M,Ozturk S,Alcelik A,Ozlu MF,Erdem A,Erdem K,Erdem FH,Yazici M

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to evaluate the influence of body mass changes on plasma concentrations of proinflammatory cytokines in obese women after the initially obtained weight reduction in a five-year follow-up period. MATERIAL AND METHODS:Thirty out of 42 women with simple obesity (age 41.8 ± 11.9 year...

journal_title：Endokrynologia Polska

authors： Olszanecka-Glinianowicz M,Chudek J,Szromek A,Zahorska-Markiewicz B

更新日期：2012-01-01 00:00:00

abstract：:The clinical manifestation of oncogenic osteomalacia includes bone pain, pathological fractures, general fatigue and muscle weakness. Such unspecific symptoms hinder the establishment of a proper diagnosis which very often requires long-lasting investigations with many diagnostic imaging methods. Here, we discuss di...

journal_title：Endokrynologia Polska

authors： Kaniuka-Jakubowska S,Biernat W,Lewczuk A,Świątkowska-Stodulska R,Sworczak K

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:The present study aims to evaluate the incidence, types, timing and risk factors in amiodarone (AMD)-induced thyroid dysfunction. MATERIAL AND METHODS:The study comprised 229 patients from an iodine-replete area (115 women, 114 men, mean age 63.8 ± 9.2 years), chronically treated with AMD. The cases were ...

journal_title：Endokrynologia Polska

authors： Zosin I,Balaş M

更新日期：2012-01-01 00:00:00

abstract：:We present the diagnostic and therapeutic difficulties encountered in a patient with a clinically advanced pancreatic neuroendocrine tumour. The report concerns a 60-year-old female patient with the diagnosis of non-functioning pancreatic neuroendocrine tumour (NET G1) with liver, peripancreatic lymph node and mediast...

journal_title：Endokrynologia Polska

authors： Rosiek V,Kunikowska J,Kos-Kudła B

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate the number of women who take multivitamin formulations containing iodine. MATERIAL AND METHODS:A 34-question questionnaire was given to 500 women during their puerperal stay in two obstetrics/gynaecology wards in Krakow. RESULTS:295 pregnant women (59%) took iodine-con...

journal_title：Endokrynologia Polska

authors： Milewicz T,Czyżewicz M,Stochmal E,Galicka-Latała D,Hubalewska-Dydejczyk A,Krzysiek J

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:We evaluated the predictive value of IGF-1 against hGH in the treatment outcome. MATERIAL AND METHODS:A prospective study was undertaken of 47 patients (mean age 41.1 ± 12.9 years; 44 with macroadenoma and 3 with microadenoma), requiring treatment with octreotide LAR (SSLAR) following incomplete surgery. Co...

journal_title：Endokrynologia Polska

authors： Bałdys-Waligórska A,Krzentowska-Korek A,Gołkowski F,Sokołowski G,Hubalewska-Dydejczyk A

更新日期：2011-01-01 00:00:00

abstract：:Elevated levels of serum glucose have deleterious effects on the walls of blood vessels, leading to microangiopathy. Such a destructive process involves also pulmonary circulation, where it is referred to as diabetic pulmonary microangiopathy. This hypothesis has been confirmed in histopathologic examinations of pulmo...

journal_title：Endokrynologia Polska

authors： Kuziemski K,Specjalski K,Jassem E

更新日期：2011-01-01 00:00:00

abstract：:Most medical agents currently applied in osteoporosis therapy act by inhibiting bone resorption and reducing bone remodelling, i.e. they inhibit the process of bone mass loss by suppressing bone resorption processes. These drugs provide an ideal therapeutic option to prevent osteoporosis progression. They however have...

journal_title：Endokrynologia Polska

authors： Misiorowski W

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Prolactin (PRL) exists in human blood in several molecular forms. Macroprolactin (MaPRL), which most often consists of monomeric PRL and immunoglobulin G, has the highest molecular weight but no biological activity. Immunoassays do not distinguish MaPRL from monomeric PRL, what can lead to an incorrect diagn...

journal_title：Endokrynologia Polska

authors： Beda-Maluga K,Pisarek H,Komorowski J,Pawlikowski M,Świętosławski J,Winczyk K

更新日期：2011-01-01 00:00:00

abstract：:The hormone leptin is secreted from white adipocytes, and serum levels of leptin correlate with adipose tissue mass. Leptin was first described as acting on the satiety centre in the hypothalamus through specific receptors (ob-R) to restrict food intake and enhance energy expenditure. Leptin plays a crucial role in th...

journal_title：Endokrynologia Polska

authors： Tucholski K,Otto-Buczkowska E

更新日期：2011-01-01 00:00:00